Osman was a 2006 Pew Fellow in the Arts, and has received grants from the National Endowment for the Arts, the New York Foundation for the Arts, The Pennsylvania Council on the Arts, the Howard Foundation, and the Fund for Poetry. She has been a writing fellow at the MacDowell Colony, the Blue Mountain Center, the Djerassi Foundation, and Chateau de la Napoule.
She founded and edited the award-winning and internationally recognized literary magazine Chain with Juliana Spahr for twelve years; Osman and Spahr now edit the ChainLinks Book series together.
Osman received an M.A. in poetry and playwriting from Brown University, and a Ph.D. in English from the Poetics Program at the State University of New York at Buffalo. She teaches in the MFA Creative Writing program at Temple University in Philadelphia.